CueZen

Digital Therapeutics + Value-Based Insurance Design: Turning Financial Incentives into Lasting Behavior Change

The next evolution of healthcare isn’t just about lowering copays – it’s about making those incentives psychologically compelling and actionable at scale.

The V-BID Boom Meets the Behavior Gap

Value-Based Insurance Design (V-BID) is expanding rapidly across healthcare. CMS has approved numerous Medicare Advantage V-BID demonstration programs that reduce or eliminate cost-sharing for high-value services like diabetes management medications, chronic disease monitoring, and preventive screenings. Employer-sponsored plans increasingly adopt similar models, recognizing that targeted financial incentives can theoretically improve health outcomes while managing long-term costs.

However, a significant gap exists between financial incentive availability and actual behavior change. Medication adherence rates for chronic conditions consistently remain around 50% across multiple systematic reviews, even when cost barriers are substantially reduced¹. Preventive care utilization often stays below optimal levels despite generous coverage improvements.

This disconnect reveals a fundamental challenge: financial incentives alone don’t reliably change behavior.

The issue isn’t the financial incentive design – it’s the missing behavioral layer that could transform economic motivation into sustained health actions.

Why Your Brain Doesn’t Care About Copay Reductions

Despite generous V-BID programs, medication adherence rates for chronic conditions remain around 50% according to systematic reviews¹. Preventive care utilization stays low even when cost-sharing is eliminated. The disconnect between financial incentives and actual behavior change reflects well-documented principles from behavioral economics research.

Thaler and Sunstein’s foundational work on choice architecture demonstrates that humans struggle with temporal discounting – the tendency to value immediate costs and benefits more heavily than future ones². A $30 copay reduction for diabetes medication might save $360 annually, but this abstract future benefit rarely competes with the immediate friction of complex medication schedules or side effects.

Research on health behavior interventions reveals several key factors for effectiveness:

Timing Matters: Just-in-Time Adaptive Interventions (JITAIs) show superior outcomes when delivered at optimal moments rather than on fixed schedules³. A medication reminder aligned with individual routines proves more effective than generic periodic messaging.

Personalization Drives Engagement: Systematic reviews of digital health interventions consistently find that personalized approaches achieve higher engagement rates than one-size-fits-all messaging⁴.

Loss Framing Effects: Meta-analyses confirm that loss-framed messages can be more motivating than gain-framed messages for certain health behaviors⁵.

Social Influence: Social comparison feedback has demonstrated effectiveness across multiple health behavior domains, though effects vary by population and context⁶.

Traditional V-BID programs reduce financial barriers but lack the behavioral intelligence to make those benefits psychologically compelling at the individual level.

From Financial Incentives to Behavioral Change: The AI Enhancement Layer
From Financial Incentives to Behavioral Change: The AI Enhancement Layer

Enter AI-Powered Behavioral Intervention

Digital therapeutics powered by artificial intelligence can transform V-BID from a blunt financial instrument into a precision behavioral tool. Rather than hoping members will spontaneously optimize their health behaviors because costs are lower, AI systems can actively guide them toward those behaviors with personalized, context-aware interventions.

The evidence for this approach comes from large-scale real-world deployments. CZ’s NudgeRank™ platform, currently operational in Singapore’s population health program, demonstrates AI-driven behavioral intervention at unprecedented scale. The system delivers personalized health nudges to over 1.1 million citizens daily through Singapore’s Healthy 365 mobile app.

A controlled study of 84,764 participants receiving personalized nudges versus 84,903 matched controls showed statistically significant improvements: 6.17% increase in daily steps and 7.61% increase in weekly moderate-to-vigorous physical activity over 12 weeks⁷. The platform achieved a 13.1% nudge open rate compared to baseline rates of 4%.

Measured Outcomes
Measured Outcomes

The system combines Graph Neural Networks with dynamic Knowledge Graphs to create comprehensive member profiles integrating demographics, clinical data, lifestyle patterns from wearables, and behavioral preferences. This enables understanding not just what behaviors to encourage, but when, how, and why to encourage them for each individual.

Key to effectiveness is real-time adaptation. The Singapore deployment processes data from 30+ wearable device types and updates behavioral interventions based on changing member contexts and preferences. The system operates entirely within Singapore’s government cloud environment, maintaining data sovereignty while scaling to population-level deployment.

The Insurance Business Case: Beyond Cost Reduction

For payers, integrating behavioral AI with V-BID programs addresses multiple business imperatives with measurable outcomes:

Operational Efficiency: The Singapore deployment achieved a 20% reduction in program management costs through AI automation while delivering improved health outcomes⁸. When member engagement increases 2.75-fold compared to standard approaches, administrative costs per successful intervention decrease substantially.

Quality Metrics Enhancement: Medicare Advantage plans face increasing pressure on STAR ratings, particularly around medication adherence and preventive care utilization. AI-powered interventions that demonstrably improve these behaviors through personalized engagement directly impact quality scores.

Scalability Without Proportional Cost Increase: Traditional health coaching requires linear scaling of human resources. AI systems can handle millions of personalized interventions daily with fixed infrastructure costs. The Singapore platform processes over 1.1 million daily nudges with a system that scales horizontally on commodity cloud infrastructure.

Measurable Health Outcomes: Controlled studies provide quantifiable evidence of intervention effectiveness. The 6.17% increase in daily steps and 7.61% increase in physical activity minutes represent concrete improvements that translate to reduced long-term healthcare utilization for chronic conditions.

Payer ROI Framework: Al-Enhanced Value-Based Insurance Design

Investment

Platform Integration

  • Azure deployment
  • EHR integration
  • Wearable device APIs

Behavioral Content

  • Nudges library development
  • Clinical protocol mapping

Operations

  • Staff training
  • System monitoring

Value Drivers

Enhanced Engagement

  • 13.1% open rate vs 4% baseline
  • Personalized nudging increases member interaction

Measurable Behavior Change

  • 6.17% ↑ steps, 7.61% ↑ MVPA
  • Controlled study with 84k participants

Operational Efficiency

  • 20% reduction in program costs
  • AI automation scales without linear staff increase

Population Scale

  • 1.1M+ daily personalized interventions
  • Proven 18+month production deployment

Business Outcomes

Quality Metrics Improvement

  • STAR ratings enhancement
  • Medication adherence scores
  • Preventive care utilization

Medical Cost Management

  • Reduced long-term claims
  • Early intervention benefits
  • Chronic disease progression

Member Experience

  • Personalized care perception
  • Reduced friction for healthy behaviors
  • 6x more “useful” than “not useful” ratings

Strategic Position

  • Differentiated V-BID offerings
  • Data-driven benefit design
  • Scalable personalization capability

Risk Mitigation

Technical Risk

  • Proven production deployment
  • Data sovereignty model

Clinical Risk

  • Evidence-based interventions
  • Controlled study validation

Regulatory Risk

  • HIPAA compliant design
  • No Pill requirements
ROI Timeline
ROI Timeline

Integration Capabilities: Modern platforms deploy entirely within payer environments, ensuring data never leaves their secure infrastructure. CZ’s platform, for example, runs in customer Azure tenants with government-grade security while integrating with existing EHR systems and wearable device ecosystems.

From Reactive Benefits to Proactive Behavior Architecture

Advanced implementations combine V-BID financial structures with evidence-based behavior change techniques. This involves moving beyond simple copay reductions to create what behavioral economists call “choice architecture” – environments that make healthy behaviors easier to adopt and maintain.

For medication adherence, documented approaches include:

  • Adaptive Timing: AI systems that learn individual response patterns and adjust reminder timing and messaging based on engagement data
  • Contextual Personalization: Interventions that account for individual schedules, preferences, and historical behavior patterns
  • Real-Time Optimization: Continuous adjustment based on wearable data, prescription pickup patterns, and user feedback

For preventive care, successful strategies involve:

  • Intelligent Scheduling: Systems that identify optimal appointment times based on individual patterns and preferences
  • Personalized Messaging: Communications adapted to individual motivations and communication preferences
  • Friction Reduction: Coordinated approaches that align financial incentives with logistical support

The NHS implementation for gestational diabetes management illustrates integration potential: unified platforms combining EHR data, digital therapeutics, and lifestyle monitoring to provide personalized interventions while reducing notification fatigue and improving care coordination.

The Technical Infrastructure for Scale

Implementing behavioral AI at payer scale requires robust technical infrastructure designed for healthcare environments. Production deployments demonstrate specific architectural requirements and capabilities.

The CZ platform exemplifies this approach, deploying entirely within customer cloud environments (Microsoft Azure tenants) to ensure complete data sovereignty while maintaining enterprise security standards. Key architectural components include:

Device Integration: Documented compatibility with 30+ wearable device manufacturers including Apple Health, Google Fit, Fitbit, Apple Watch, and major fitness tracker brands through unified API interfaces.

Privacy-First Design: Systems operate without any Personal Identifiable Information (PII), using pseudonymous masked IDs throughout. All processing occurs within customer environments with no data egress to external systems.

Scalability Evidence: CZ’s Singapore deployment processes over 1.1 million daily personalized interventions using a 10-node Kubernetes cluster, with linear scaling demonstrated up to 19 billion candidate user-nudge pairs.

Automated Operations: Daily model updates completing in 90-150 minutes, with 18+ months of continuous production operation demonstrating system reliability and automated failure recovery.

Healthcare Integration: Proven integration with EHR systems (demonstrated in NHS gestational diabetes management) and existing payer infrastructure without disrupting operational workflows.

These technical capabilities matter because payer adoption requires confidence that behavioral AI can integrate with existing systems without compromising security or operational stability.

The Strategic Imperative: Integration, Not Addition

The healthcare industry’s tendency toward fragmented point solutions has created intervention fatigue among both providers and members. The winning approach integrates behavioral science directly into existing V-BID structures rather than adding another layer of complexity.

This means viewing digital therapeutics not as separate wellness programs, but as the behavioral intelligence layer that makes V-BID programs effective. Instead of hoping members will respond to financial incentives, payers can actively orchestrate the behavioral change those incentives are designed to encourage.

Forward-thinking payers are already moving in this direction. The convergence of V-BID expansion, AI capabilities maturation, and growing evidence of population-scale behavioral intervention effectiveness creates a narrow window for competitive advantage.

Value-Based Insurance Design Evolution
From Concept to Population-Scale Implementation with AI Enhancement
Value-Based Insurance Design Evolution
From Concept to Population-Scale Implementation with AI Enhancement

Current V-BID Implementation Impact

50+

Medicare Advantage Plans
Participating in CMS V-BID demonstrations

Growing

Employer Adoption
Large employers implementing V-BID strategies

Multi-State

Medicaid Programs
State-level V-BID initiatives expanding

The Al Enhancement Opportunity

While V-BID programs have demonstrated promise in reducing financial barriers, Al-powered behavioral intervention represents the next evolution-transforming financial incentives into sustained behavior change through personalized context-aware digital therapeutics at population scale.)

The Path Forward: Five Strategic Actions

  1. Audit Current V-BID Utilization: Identify programs with low engagement despite generous financial incentives – these represent immediate opportunities for behavioral enhancement.
  2. Pilot Behavioral AI Integration: Start with high-impact, measurable use cases like medication adherence or diabetes management where both financial and health outcomes are easily tracked.
  3. Invest in Behavioral Analytics: Develop capabilities to measure not just clinical outcomes, but behavioral engagement, intervention effectiveness, and member satisfaction with personalized approaches.
  4. Design for Cultural Competence: Ensure AI systems can adapt to diverse member populations, supporting health equity goals while improving overall effectiveness.
  5. Plan for Scale: Choose platforms and partnerships that can grow from pilot programs to population-scale deployment without requiring fundamental architecture changes.

Conclusion: Beyond Incentives to Influence

Value-Based Insurance Design represented a crucial evolution from fee-for-service to outcome-focused healthcare financing. However, evidence suggests financial incentives alone cannot bridge the gap between knowing what to do and actually doing it.

The documented success of AI-powered behavioral interventions – demonstrated through controlled studies with tens of thousands of participants – shows that integrating behavioral science with financial incentives can make those incentives more effective. This isn’t about replacing V-BID programs, but enhancing them through behavioral intelligence that was previously unavailable.

Real-world deployments prove that AI-powered behavioral interventions can drive measurable health improvements at population scale. For payers, the question becomes how to integrate these proven capabilities with existing V-BID structures to maximize both member health outcomes and program effectiveness.

The evolution from financial incentives to behavioral influence represents a practical next step for healthcare organizations seeking to improve both clinical outcomes and operational efficiency.

The convergence of behavioral science, artificial intelligence, and value-based care represents healthcare’s next frontier. Organizations ready to move beyond traditional incentives to intelligent influence will define the industry’s next decade.

References:

1. Vrijens, B., et al. (2017). A comprehensive overview of medication adherence in middle-aged and elderly patients. European Heart Journal, 38(14), 1038-1047.
2.Thaler, R. H., & Sunstein, C. R. (2008). Nudge: Improving decisions about health, wealth, and happiness. Yale University Press.
3.Nahum-Shani, I., et al. (2018). Just-in-time adaptive interventions (JITAIs) in mobile health: key components and design principles for ongoing health behavior support. Annals of Behavioral Medicine, 52(6), 446-462.
4. Lustria, M. L. A., et al. (2013). A meta-analysis of web-delivered tailored health behavior change interventions. Journal of Health Communication, 18(9), 1039-1069.
5. Gallagher, K. M., & Updegraff, J. A. (2012). Health message framing effects on attitudes, intentions, and behavior: a meta-analytic review. Annals of Behavioral Medicine, 43(1), 101-116.
6. Cialdini, R. B., et al. (2006). Managing social norms for persuasive impact. Social Influence, 1(1), 3-15.
7. Chiam, J., Lim, A., & Teredesai, A. (2024). NudgeRank: Digital Algorithmic Nudging for Personalized Health. KDD ’24 Conference Proceedings.
8. CZ Platform Documentation (2025). Singapore Health Promotion Board Population Health Program Results.

Author:

Novex Alex Human behavior fascinates me—beautifully complex and unsolved, caught between our evolutionary instincts and today's rapidly changing world. There's a persistent gap between what's good for us, what we want, and what we actually do. Today's AI mirrors these same contradictions, yet tomorrow's self-learning technologies hold promise. I'm driven to embrace human diversity and complexity by building adaptive systems that meet people where they are, unlocking small personal changes without compromising autonomy. This approach isn't just compassionate—it's how each person's breakthrough becomes part of humanity's path to lasting transformation.

How Do ID-Free Models Stack Up? A Performance Benchmark Against Our Current ID-Based RecSys

In our previous post, “From IDs to Meaning: The Case for Semantic Embeddings in Recommendation,” we introduced the concept of moving beyond ID-based representations to metadata-driven approaches and why it’s promising for domains like digital health and personalized health, where personalization needs to go beyond static IDs. By leveraging semantic embeddings derived from descriptive metadata using Large Language Models (LLMs), ID-free approaches aim to address common challenges such as cold-start problems, limited generalizability, and deployment complexity.

In this post, we move from concept to evidence. Our central question is: How do standard recommendation architectures perform when powered by ID-free semantic embeddings, compared to our current ID-based Knowledge Graph Attention Network (KGAT) recommender model?

Models Compared

For this evaluation, we selected models that reflect two distinct approaches to user and nudge representation: Baseline Models (both non-embedding and ID-based) and ID-Free Enhanced Models.

Baseline Models

These models serve as foundational benchmarks for evaluating the value of more advanced, semantic embedding driven approaches:

  • Random: A basic, non-personalized baseline that sets the lower bound for performance, whereby nudges are randomly selected for users.
  • Popular: A simple heuristic that recommends items based on how frequently they were interacted with across the entire available history. This provides a static, global view of popularity and serves as a non-personalized baseline. While it doesn’t use embeddings or user-specific information, it offers a useful reference point for evaluating the performance of learned models.
  • Knowledge Graph Attention Network (KGAT): Our current production model, KGAT, uses the traditional ID-based approach in a Graph Neural Network (GNN). It assigns unique numerical identifiers to each entity (e.g. users, nudges, markers, segments) within a knowledge graph and learns dedicated embeddings for each. An attention mechanism allows the model to capture complex, multi-hop relationships, making it especially effective at leveraging structured knowledge and explicit interaction histories, thereby serving as a strong ID-based benchmark [1]. This model has been successfully personalizing nudges for millions of participants daily, with very good results [2].

ID-Free Enhanced Models Leveraging Metadata

These models represent traditional, well-established recommendation architectures, but with a key change: instead of learning embeddings from arbitrary IDs, they are adapted to operate on pre-computed semantic embeddings. These embeddings are generated using LLMs applied to rich metadata—such as user health profiles, behavioral signals, and nudge content—allowing us to directly assess how well semantic inputs perform when integrated into widely adopted architectures. The following models were selected as they represented a spectrum of RecSys architectures from collaborative filtering to sequential recommenders.

  • BPR (Bayesian Personalized Ranking): A classic pairwise ranking model for collaborative filtering, optimized for implicit feedback [3].
  • NeuMF (Neural Matrix Factorization): A neural network-based approach for collaborative filtering, combining matrix factorization and multi-layer perceptron layers [4].
  • SimpleX: A lightweight yet performant collaborative filtering model that incorporates historical user-item interaction sequences [5].
  • SASRec (Self-Attentive Sequential Recommendation): A state-of-the-art sequential recommendation model that leverages self-attention over item sequences to capture dynamic behavioral patterns [6].

Experiment Setup

To ensure a robust and fair comparison, we conducted our experiments on our proprietary digital health recommendation dataset. The dataset encompasses 10 days of user interactions with various health nudges, alongside rich metadata for both users (e.g., demographics, health conditions, aggregated tracker data) and nudges (e.g., content text, categories, target behaviors, health nudges).

The following table summarizes the dataset statistics used for all models during training, validation, and testing.

StatisticOverallTrainValidationTest
# Users 3,069 2,558 445 446
# Nudges 70 68 47 42
# Interactions 4,490 3,599 445 446

Table 1: Dataset Statistics for Overall, Train, Validation, and Test sets.

The ID-based KGAT model, unlike the other models, represents users, nudges, and related entities within a structured knowledge graph or health graph. As a result, its input includes a larger set of interconnected entities and relation types:

StatisticKGAT Input
# Nodes79,447
# Edges564,429

Table 2: Knowledge Graph Structure for the KGAT Model.

Our evaluation followed a standard protocol:

  • Data Split: The dataset was split based on time into training, validation, and test sets using an 80/10/10 ratio. For sequential models, interactions were chronologically ordered, with the last interaction used for testing.
  • Hyperparameter Tuning: Optimal hyperparameters for each model were determined based on maximizing NDCG@3 on the validation set. 100 trials (hyperparameter combinations) were evaluated for each model, using Asynchronous Successive Halving Algorithm (ASHA) [7] to optimize the search.
  • Training and Evaluation: All models were trained until convergence, with early stopping implemented to prevent overfitting. Performance metrics were computed on the held-out test set.

Key Differences in Metadata and Input Representation

To fully appreciate the distinct behaviors and performances observed in our benchmark, it is important to understand the fundamental differences in how our ID-based and ID-Free Enhanced models consume and represent data—especially in how they capture semantics, structure, and temporal context.

The ID-based KGAT model builds a knowledge graph where users, nudges, and related entities (e.g., markers, segments) are represented as unique nodes. Relationships between these nodes (e.g., has_marker, in_segment) form the graph’s edges. This structure allows the model to learn from multi-hop connections and structured metadata, but it encodes user and nudge attributes as a fixed snapshot, based on their state at the beginning of the input window.

In contrast, ID-free models use semantic embeddings that are dynamically generated from rich metadata at the time of each interaction. For example, a user’s embedding is derived from their behavioral attributes at the time the nudge was sent, while a nudge’s embedding reflects its actual content at the time (in case of any edits). This enables the model to adapt to temporal changes and deliver personalized recommendations using up-to-date information.

The table below summarizes key differences in how users and nudges are represented across the two approaches:

AspectKGATID-Free Enhanced Models
Interaction DataConsiders only the distinct nudges a user has interacted with (duplicates removed).Includes all interactions, including repeated nudges, in the user's history. Sequential models also capture the order of interactions.
Temporal AdaptabilityStatic
• Users and nudges are represented as a point-in-time snapshot based on their attributes at the start of the input window.
• Limits the number of days of interaction data to avoid misalignment between interactions and associated user or nudge attributes (e.g. user health behaviors that change daily).
Dynamic
• Semantic embeddings of users and nudges are updated as their attributes change.
• Interactions are mapped to user and nudge embeddings using point-in-time joins, to associate an interaction event with the temporally-correct representation of the user and nudge.
• No restriction on the amount of historical data used, since representations can reflect current states at any time.
User RepresentationGraph-based connections to attributes (markers) and segments.Semantic embeddings from the user's current attributes.
Nudge RepresentationGraph-based connections to nudge attributes and target segments.Semantic embeddings from the actual nudge content.

Evaluation Metrics

We assessed performance using standard top-K recommendation metrics, specifically at K=3. These metrics quantify the quality of the top-ranked recommendations:

  • NDCG@3 (Normalized Discounted Cumulative Gain): Measures the ranking quality, assigning higher scores to relevant items that appear earlier in the recommendation list.
  • Precision@3: The proportion of recommended items at K=3 that are relevant.
  • Recall@3: The proportion of all relevant items successfully retrieved within the top K=3 recommendations.
  • MAP (Mean Average Precision): A measure that provides a comprehensive summary of overall ranking quality across different relevance thresholds.

The Results: Unpacking the Benchmark

Let’s dive into how the models performed. The chart below presents the recommendation performance for each model across the key metrics.

Model Performance: ID-Based vs. ID-Free Models

Key Observations

  • Value of Personalization: KGAT and all ID-Free models consistently performed better than the Random and Popular baselines across all metrics, reaffirming the importance of personalization and context-aware recommendations.
  • Baselines Provide Context: As expected, the Random baseline delivered the lowest performance across all metrics, establishing a clear lower bound. The Popular baseline significantly outperformed Random, demonstrating the effectiveness of popularity-based heuristics on this particular dataset.
  • KGAT’s Performance: Our ID-based KGAT model remained a strong performer compared to the non-personalized baselines, demonstrating the power of modeling deep, multi-hop relationships through attention over a knowledge graph. However, it was generally outperformed by the ID-free models across all metrics—highlighting the added value of semantic inputs and dynamic context.
  • ID-Free Models Showcase Potential: The ID-Free Enhanced models (BPR, NeuMF, SimpleX, SASRec) generally performed on par with or better than KGAT, indicating the potential of semantic embeddings in capturing richer behavioral context.
    • Among the ID-Free models, BPR, SimpleX, and SASRec showed similar levels of performance, demonstrating their ability to effectively leverage semantic embeddings.
    • NeuMF clearly stood out in this experiment, delivering the strongest performance across all metrics. Its hybrid architecture—combining matrix factorization with neural layers—appears particularly well-suited to capturing the semantic richness of ID-Free embeddings.

Discussion: Insights from the Benchmark

These results suggest promising potential for ID-free embeddings to reshape how we approach recommendations—especially in dynamic, highly personalized domains like digital health, where user behaviors and preferences change on a daily basis. We repeated the experiments across multiple date ranges and consistently observed similar performance patterns, reinforcing the reliability of these insights.

Several key insights stand out:

  • The Power of Semantic Understanding: ID-free embeddings—derived from descriptive metadata like nudge content and user health profiles—enable models to capture richer, more meaningful relationships than purely ID-based representations. This semantic grounding supports better generalization and adaptability, which is critical in contexts where user behaviors and nudge content are constantly evolving.
  • Enhancing Existing Architectures: A key takeaway is that traditional, well-understood architectures like NeuMF and SASRec can achieve strong results when powered by high-quality ID-free embeddings. This opens up opportunities to modernize recommendation pipelines without requiring wholesale changes to core infrastructure or training paradigms.
  • Complementary Strengths Across Models: While the ID-Free Enhanced models performed better than KGAT, KGAT remained a strong contender—particularly in its ability to model complex, multi-hop relationships through structured knowledge graphs and health graphs. Its strength lies in leveraging curated domain knowledge and explicit relationships, which can be particularly valuable when semantic metadata is limited or noisy. Meanwhile, ID-free models benefit from greater adaptability to changing user contexts and can scale easily without requiring graph maintenance. These findings suggest that future improvements may come from hybrid approaches that combine the structured reasoning of graph-based models with the flexibility and semantic depth of ID-free embeddings.

What’s Next?

This benchmark marks a pivotal step in our journey toward more adaptive and scalable recommendation systems. The strong performance of ID-Free Enhanced models signals a promising direction for the future of personalized digital health nudging. Our next steps will focus on:

  • Evaluating the performance of the ID-free models across varying training data sizes to understand trade-offs between model performance, training time, and resource consumption.
  • Conducting ablation studies and detailed evaluations to explore factors such as the robustness of semantic embeddings, the impact of negative sampling strategies, optimal sequence length, pruning historical items, and the choice of embedding models and role of metadata.

These explorations will help us further assess the practical value of ID-free modeling and unlock its full potential—guiding our efforts to build an even more personalized, effective, and scalable nudge engine for digital health and personalized health.

References:

[1] X. Wang and e. al., “KGAT: Knowledge Graph Attention Network for Recommendation,” in KDD ’19, 2019.
[2] J. Chiam and e. al., “NudgeRank: Digital Algorithmic Nudging for Personalized Health,” in KDD ’24, 2024.
[3] S. Rendle and e. al., “BPR: Bayesian personalized ranking from implicit feedback,” in UAI ’09, 2009.
[4] X. He and e. al., “Neural Collaborative Filtering,” in WWW ’17, 2017.
[5] K. Mao and e. al., “SimpleX: A Simple and Strong Baseline for Collaborative Filtering,” in CIKM ’21, 2021.
[6] W.-C. Kang and e. al., “Self-Attentive Sequential Recommendation,” in ICDM ’18, 2018.
[7] L. Li and e. al., “A System for Massively Parallel Hyperparameter Tuning,” in MLSys 2020, 2020.

From IDs to Meaning: The Case for Semantic Embeddings in Recommendation

Recommender systems have become indispensable for navigating the vast digital landscape, helping users sift through large volumes of content, products, and services. In the realm of digital health, they play an increasingly vital role in delivering personalized nudges and guidance, enhancing individual engagement, and supporting better health outcomes.

Traditionally, these systems rely on ID-based embeddings, where each user and item (or in our case, each individual and health nudge) is assigned a unique numerical identifier. These IDs are then converted into dense vector representations using techniques like matrix factorization or collaborative filtering. While effective for individuals with interaction histories and popular nudges, this approach has notable limitations, particularly around generalizability and cold-start scenarios.

Enter ID-free embeddings: a promising shift enabled by advances in Large Language Models (LLMs). Instead of relying on arbitrary IDs, these embeddings are generated directly from the rich, descriptive metadata associated with individuals and health nudges—think nudge content (e.g., text, language, tonality), individual health behavior data (e.g., fitness tracker data, dietary logs), demographic data, and health conditions. By leveraging the advanced semantic understanding capabilities of LLMs, ID-free embeddings capture the inherent meaning and relationships within this textual and behavioral information, offering a more flexible and robust foundation for personalized health recommendations.

Why Move Away from ID-Based Embeddings?

While conventional ID-based embeddings have been the mainstay of recommender systems for decades, it has several limitations:

  1. Cold start: New users or nudges without historical data tend to perform poorly, as the system lacks enough context to generate meaningful recommendations. This leads to a poor initial experience for new users and slower adoption of new nudges.
  2. Overfitting to history: Models often memorize frequent users or nudges, reducing their ability to generalize.
  3. Limited portability: These models are transductive in nature, learning about specific users and nudges, and struggle to generalize to new or unseen ones. For example, user 123 in Deployment A of NudgeStream is a distinct individual from user 123 in Deployment B, so the models learned at each deployment cannot be easily transferred across deployments or use cases.
  4. Operational complexity: ID-based pipelines often require custom retraining and tracking, since user and nudge IDs are unique to each deployment or population.

What is ID-Free Embeddings?

At their core, ID-free embeddings transform the descriptive text and structured data associated with individuals and health nudges into high-dimensional numerical vectors, using a pre-trained LLM encoder. For example, a nudge like “Need a snack? Choose crunchy veggies like carrots to curb hunger without the calories.” Is fed into the LLM, which then outputs a dense vector representing the semantic essence of that nudge. Similarly, an individual’s health profile, including their activity levels from a fitness tracker, dietary preferences, or health goals, can be encoded into an individual embedding. This process allows the recommender system to understand what a nudge is designed to achieve, or who an individual is, based on their attributes and behaviors, rather than just a unique identifier.

In CueZen’s recommender setup:

  • User embeddings represent the individual’s current context, derived from a combination of static attributes (e.g. demographics) and dynamic attributes (e.g. recent health behaviors from tracker data).
  • Item embeddings represent the nudge content itself. For example, a message like “a gentle reminder to take a 10-minute walk after lunch to boost energy” is encoded into a vector that captures its semantic meaning, such that nudges with similar messages or goals have similar embeddings. 

The diagram above illustrates the differences between ID-based and ID-free embeddings. ID-based embedding vectors are created and randomly initialized for every unique individual and nudge. These embeddings are then iteratively updated (along with the model weights) during the training process of the recommender model, such that they optimize some objective or loss function. In the case of ID-free embeddings, user and nudge metadata are transformed into semantic embeddings via a pre-trained LLM, using only semantic content and not requiring any IDs. Model training proceeds as usual, where model weights are iteratively updated to optimize the objective or loss function.

Benefits of ID-Free Embeddings

This semantic approach offers several advantages for building robust and effective digital health recommender systems:

  1. Eliminating cold-start scenarios: Semantic embeddings can be computed for new users or nudges and directly plugged into a recommender model without requiring interaction history [1]. This means relevant recommendations can be made even for brand new users or nudges right out of the gate, leading to a much more engaging initial experience.
  2. Enhanced Generalization and Universal Representations: ID-free embeddings provide universal representations that generalize across different populations and deployments. For example, two individuals from different countries—both 35 years old, prediabetic, overweight, and sedentary—would have similar embeddings. Similarly, two nudges containing the same topic and advice would have similar embeddings even if they were written in different languages. This allows models to learn patterns from the underlying behavior and content, leading to strong performance on previously unseen users or nudges and mitigating the problem of overfitting to historical data [2].
  3. Improved Transferability and Simplified Deployment: Because these embeddings capture intrinsic meaning rather than arbitrary IDs, models trained on one population and use case can transfer effectively to others, delivering good results from day one [3]. Fine-tuning on the target population can further enhance recommendation performance. This also simplifies model deployment, as precomputed embeddings remove the need for ID-specific retraining or the tracking of large ID-based embedding matrices across different deployments.
  4. Reusability of Existing Recommender Architectures: A practical benefit is that many existing recommender architectures can be directly reused, by simply replacing the randomly initialized ID-based embedding matrix with precomputed semantic embeddings. ID-free embeddings can be integrated seamlessly into the vast body of existing recommender models and proven architectures, without needing to reinvent the wheel.
  5. Privacy-Aware Design: By reducing dependence on personal identifiers and focusing on semantic attributes, this approach inherently supports safer handling of sensitive customer health data.

Related Work

Recommender systems using ID-free embeddings are a rapidly evolving area of research. Built on the strong foundations of “traditional” recommender systems, the use of LLMs opens up many new possibilities in addressing previous limitations such as cold start, transferability and generalization across domains. As a result, researchers are increasingly interested in ID-free or modality-based approaches, which leverage semantic embeddings derived from content or behavioral signals.

The foundation for semantic retrieval models was laid by early neural recommender systems like DSSM [4] and the Youtube DNN model [5], which introduced architectures to map users and items into shared embedding spaces using behavioral and content features. Further advancements, such as Two-tower models [6] and attention-based architectures like DIN [7] and DIEN [8], significantly enhanced the ability to model user intent without relying solely on explicit ID representations.

Recent progress has pushed this direction further by demonstrating strong performance using purely semantic inputs. For instance, large language models (LLMs) have achieved state-of-the-art results for collaborative filtering using only textual item descriptions [9]. Similarly, Recformer [10] learns sequential user preferences by applying language modeling techniques directly to item content, thereby bypassing traditional ID lookups entirely.

Zero-shot and transferrable recommendation is another emerging area. ZESRec [11] performs well on cold-start tasks without requiring historical user data, while universal representation learning (UniSRec) [12] and vector-quantized embeddings (VQ-Rec) [13], demonstrate improved generalization across users and domains.

From a broader perspective, [14] present a comparative study between ID-based and modality-based recommenders, concluding that semantic models are not only viable alternatives but, in some cases, superior—especially in sparse or evolving environments. These findings align with our motivation to adopt ID-free recommendation strategies based on behavioral and content embeddings.

What’s Next?

In the next few posts, we’ll go deeper into the following:

  • Comparing our existing ID-based Knowledge Graph Attention Network (KGAT) model with new ID-free approaches.
  • Evaluating performance of the ID-free models across varying training data sizes.
  • Additional ablation studies and evaluations on the robustness of semantic embeddings.

These explorations will help us assess the practical value of ID-free models and guide our next steps in improving our nudge engine. 

References:

[1] S. Sanner and e. al., “Large Language Models are Competitive Near Cold-start Recommenders for Language- and Item-based Preferences,” in RecSys, 2023.
[2] K. Zhang and e. al., “Learning ID-free Item Representation with Token Crossing for Multimodal Recommendation,” arXiv, 2024.
[3] Y. Li and e. al., “A Zero-Shot Generalization Framework for LLM-Driven Cross-Domain Sequential Recommendation,” arXiv, 2025.
[4] P.-S. Huang and e. al., “Learning deep structured semantic models for web search using clickthrough data,” in CIKM, 2013.
[5] P. Covington and e. al., “Deep Neural Networks for YouTube Recommendations,” in RecSys, 2016.
[6] X. Yi and e. al., “Sampling-bias-corrected neural modeling for large corpus item recommendations,” in RecSys, 2019.
[7] G. Zhou and e. al, “Deep Interest Network for Click-Through Rate Prediction,” in KDD, 2018.
[8] G. Zhou and e. al., “Deep interest evolution network for click-through rate prediction,” in AAAI, 2019.
[9] R. Li and e. al., “Exploring the Upper Limits of Text-Based Collaborative Filtering Using Large Language Models: Discoveries and Insights,” arXiv, 2023.
[10] J. Li and e. al., “Text Is All You Need: Learning Language Representations for Sequential Recommendation,” arXiv, 2023.
[11] H. Ding and e. al., “Zero-Shot Recommender Systems,” Amazon Scienc, 2021.
[12] Y. Hou and e. al., “Towards Universal Sequence Representation Learning for Recommender Systems,” in KDD, 2022.
[13] Y. Hou and e. al., “Learning Vector-Quantized Item Representation for Transferable Sequential Recommenders,” in WWW, 2023.
[14] Z. Yuan and e. al., “Where to Go Next for Recommender Systems? ID- vs. Modality-based Recommender Models Revisited,” arXiv, 2023.

CueZen raises $5m Seed Funding to Transform Health Personalization

Point72 Ventures, with participation from Pack VC, Forston VC, and Nextinfinity have backed CueZen with an investment of US$ 5 M. This funding will enable CueZen to accelerate customer acquisition efforts and enhance platform capabilities for health enterprises looking to personalize their digital offerings.
At CueZen, we are committed to making health and wellness truly personal – because that’s where real change begins. This investment is not just fuel for growth – it’s a signal of market readiness for AI that turns everyday lifestyle and clinical data into actions that help millions improve their health. We will leverage this capital to expand our enterprise partnerships, deepen platform capabilities, and unlock measurable ROI — all while delivering personalization in health at unprecedented scale.
Ankur Teredesai
CEO of CueZen and Professor at the University of Washington.
We believe CueZen is addressing a significant gap in the digital health ecosystem. Their platform has the potential to fundamentally change how health data is leveraged across the industry. We're impressed by the early impact they've demonstrated and are excited to support their vision of creating better health outcomes while enabling new revenue streams for technology companies and providers in this space.
Tara Stokes
Partner at Point72 Ventures

CueZen at HIMSS 2025

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    The Digital Health divide is growing. Data collected from sensors and wearables by itself is not actionable. Outcomes will not improve until we change behavior.

    CueZen enables sustained and actionable behavior change for your population and your offerings. Connect with us to explore how personalization leads to proactive care.

    Connected solutions:
    2B smart wearables by 2027

    Health outcomes:
    through behavior change at national scale

    CueZen’s AI-powered performance suite is the go to platform for enterprises creating value from personalized health engagement that drives outcomes.
    Explore how you can access curated ecosystems of sensors, biomarkers, engaged communities, and clinically validated programs. Our comprehensive solution seamlessly integrates the CueStream personalized engagement system to drive timely, impactful actions.
    HIMSS is the premier digital health event where innovative solutions and experts share key insights. It brings together healthcare providers, governments, startups, and other health services organizations for engaging discussions and networking. HIMSS is committed to reforming the global health ecosystem through the power of information and technology.

    CueZen's Personalization Suite

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    for enterprises creating value from personalized health engagement that drives outcomes.

    CueZen is a winner in the Emerge Innovation Experience Contest!

    Catch us at the Emerge Innovation Experience 2025, a HIMSS 2025 debut, high-impact program that brings together health innovators, investors, and executives who will be instrumental in building the future of healthcare.

    Ready to explore the future of personalized health engagement?

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      Share this:

      The Digital Health divide is growing. Data collected from sensors and wearables by itself is not actionable. Outcomes will not improve until we change behavior.

      CueZen enables sustained and actionable behavior change for your population and your offerings. Connect with us to explore how personalization leads to proactive care.

      Connected solutions: 2B smart wearables by 2027

      Health outcomes through behavior change at national scale

      CueZen’s AI-powered performance suite is the go to platform for enterprises creating value from personalized health engagement that drives outcomes.
      Explore how you can access curated ecosystems of sensors, biomarkers, engaged communities, and clinically validated programs. Our comprehensive solution seamlessly integrates the CueStream personalized engagement system to drive timely, impactful actions.
      ViVE is the premier digital health event dedicated to driving transformation in healthcare, bringing together C-suite executives, senior digital health leaders, startups, investors, patient advocates, and solution providers to shape the industry’s future.

      CueZen AI-powered Performance Suite

      The go-to platform

      for enterprises creating value from personalized health engagement that drives outcomes.

      Ready to explore the future of personalized health engagement?

      Revolutionizing Population Health with NudgeRank™: The Future of Personalized AI-Driven Health Nudges

      The promise of artificial intelligence (AI) in healthcare has always been tantalizing. We’ve seen AI make strides in diagnostics, drug discovery, and even in the management of chronic diseases. But one area where AI is poised to make an even more profound impact is in the realm of behavior change—specifically, how we can influence health behaviors at a population level. Enter NudgeRank™—a groundbreaking tool that harnesses the power of AI to deliver personalized health nudges on an unprecedented scale. Let’s dive into how this innovation works, why it matters, and what it could mean for the future of healthcare. 

      The Herculean Task of Changing Health Behaviors

      Changing patient behavior is one of the most formidable challenges in healthcare. Research shows that approximately 70% of premature deaths are linked to behaviors that can be modified, such as smoking, poor diet, and physical inactivity. For instance, smoking cessation alone could prevent 90% of lung cancers, but only about 7% of smokers succeed in quitting on their first attempt. Similarly, adherence to medication regimens is alarmingly low; studies estimate that nearly 50% of patients with chronic diseases in developed countries do not take their medications as prescribed, leading to increased hospitalizations and healthcare costs. These behaviors are difficult to change due to a complex interplay of factors—habits are deeply ingrained, motivation can diminish over time, and everyday life often presents barriers to maintaining healthy choices.

      The World Health Organization (WHO) defines the burden of disease as the impact of a health problem measured by financial cost, mortality, morbidity, or other indicators. It reflects the gap between a population’s current health status and an ideal situation where everyone lives into old age, free of disease and disability. Behavior-related conditions like cardiovascular diseases, diabetes, and respiratory disorders contribute significantly to the global burden of disease. These conditions not only affect individual health but also place a substantial strain on healthcare systems, highlighting the critical need for effective behavior change interventions at a population level.

      Traditional public health approaches—think mass media campaigns, pamphlets, and one-size-fits-all advice—often miss the mark. They fail to account for the unique circumstances of each individual, which is where the need for personalization becomes glaringly evident. What if we could tailor health advice to each person’s specific situation, habits, and needs? That’s the question NudgeRank™ is answering with a resounding “yes.”

      NudgeRank™: Where AI Meets Personalized Health Interventions

      NudgeRank™ is not your typical AI system. It’s a sophisticated digital nudging platform designed to influence health behaviors by delivering personalized, context-aware recommendations to millions of users. At its core, NudgeRank™ combines the predictive prowess of Graph Neural Networks (GNNs) with the dynamic adaptability of a Knowledge Graph, creating a system that learns, evolves, and optimizes its interventions over time.

      Graph Neural Networks (GNNs): Graph Neural Networks are a powerful class of models that operate on graph-structured data, where entities (nodes) and their relationships (edges) can be represented in a more meaningful and flexible way than traditional grid-like data structures such as images or sequences. In NudgeRank™, the entities might be users, health interventions, behavioral goals, or nudges while the edges represent the relationships between these entities—how a user’s past behaviors might influence their future actions, or how certain interventions might be more effective based on demographic factors.

      The essence of a GNN lies in its ability to perform message passing between nodes. Each node aggregates information from its neighbors, allowing the network to learn rich, context-sensitive representations of each entity based on higher-order relationships in the knowledge graph. In the context of NudgeRank™, this means that the system can learn which factors are most predictive of a successful health nudge. For example, a GNN might learn that users who have recently been more active but are starting to lapse respond well to motivational messages tailored to their previous high performance.

      The GNN in NudgeRank™ uses a multi-layer architecture where each layer corresponds to a different level of abstraction. The initial layers might focus on simple features like the user’s age or activity level, while deeper layers capture more complex patterns such as the interaction effects between multiple health interventions. This hierarchical processing allows NudgeRank™ to build a nuanced understanding of each user’s unique circumstances.

      The model’s attentive graph convolution layers are particularly crucial. These layers enable the GNN to weigh the importance of different nodes and edges, dynamically adjusting which information is most relevant in recommending a successful health nudge at any given time. For instance, if a user’s recent behavior suggests a decline in physical activity, the model can prioritize nudges that have historically been effective for similar patterns, ensuring that interventions are timely and contextually appropriate.

      Knowledge Graph Integration: A Knowledge Graph is much more than a static database, it’s a dynamic structure that continuously evolves as new data is introduced. In NudgeRank™, the Knowledge Graph is populated with information from various sources—demographic data, historical health behaviors, interactions with past nudges, and even external data from wearables or health records. Each user’s data forms a personalized subgraph within the larger structure, with nodes representing their attributes and behaviors, and edges denoting relationships such as “increased activity after receiving a motivational nudge.”

      What makes this integration so powerful is the extensibility of the Knowledge Graph. It’s designed to easily incorporate new types of data as they become available, allowing the system to adapt and improve over time. This is particularly important in healthcare, where new information—such as updates to a user’s medical history or the introduction of new health guidelines—can significantly alter the relevance of certain interventions.

      Moreover, the Knowledge Graph is heterogeneous, meaning it includes a variety of node and edge types. For example, a node could represent a user’s demographic group, while another might represent a specific health goal like “increasing daily steps.” The edges between them could capture relationships such as how often the user met their step goals after receiving a certain type of nudge. This richness in representation allows NudgeRank™ to make more informed decisions about which nudges to prioritize, based on a deep, contextual understanding of the user’s situation.

      The combination of GNNs and Knowledge Graphs in NudgeRank™ represents a significant advance in how we can personalize health interventions at scale. By leveraging the structure and relationships within the data, NudgeRank™ doesn’t just push generic health advice—it delivers finely-tuned, data-driven nudges that are optimized for each individual, adapting in real-time to changes in behavior and context.

      Real-World Impact: Scaling Health Interventions in Singapore 

      NudgeRank™ isn’t just a theoretical model; it’s already making a difference in the real world. In Singapore, the Health Promotion Board integrated NudgeRank™ with their Healthy 365 app, a platform used by over a million citizens to track their health activities. The goal? To encourage healthier behaviors across the nation.

      The results have been impressive: users who received personalized nudges experienced a 6.17% increase in daily steps and a 7.61% increase in weekly exercise minutes, compared to those who did not receive nudges.

      NudgeRank™ achieves this through a robust, scalable architecture. The system operates within a Kubernetes cluster, enabling it to process data for millions of users in real time. It’s designed to handle up to 19 billion user-nudge pairs, ensuring that as the user base grows, the system remains responsive and effective.

      What This Means for Healthcare Providers

      For healthcare professionals, the implications of NudgeRank™ are significant. Imagine being able to ensure that your patients are receiving tailored advice and reminders that actually resonate with them—without adding to your workload. NudgeRank™ does this by automating the delivery of personalized nudges, freeing up clinicians to focus on more complex tasks that require human expertise.

      Enhanced Patient Engagement: We’ve long known that engaged patients are healthier patients. NudgeRank™ significantly boosts patient engagement by delivering nudges that are precisely calibrated to each individual’s current state. This isn’t a generic reminder to take more steps—it’s a targeted suggestion based on real-time data that’s been fine-tuned to maximize impact.

      Improved Clinical Outcomes: The relationship between patient engagement and positive health outcomes is well documented. With NudgeRank™, the connection is even more direct. By encouraging small, incremental changes that build over time, the system helps patients achieve better health outcomes, whether it’s managing a chronic condition or simply staying active.

      Operational Efficiency: Healthcare systems are under constant pressure to do more with less. NudgeRank™ helps by automating a process that’s both time-consuming and crucial—keeping patients on track with their health goals. The system’s robust design includes automated feedback loops, ensuring that it learns from each patient interaction to refine future nudges.

      Implications for the Wearables and Digital Health Industry

      The rise of wearable technology and digital health platforms has transformed how we monitor and manage our health. Devices like smartwatches, fitness trackers, and even connected home health devices generate a wealth of data that offers unprecedented insights into our daily lives. But the real value of this data lies in how it’s used to influence behavior and improve health outcomes—a challenge that NudgeRank™ is uniquely positioned to address.

      Bridging the Gap Between Data and Action: Wearables have become ubiquitous, with millions of users tracking everything from their steps and sleep patterns to heart rate and blood oxygen levels. Yet, while these devices collect vast amounts of data, translating that data into actionable health improvements has been a significant challenge. This is where NudgeRank™ comes into play.

      NudgeRank™ bridges the gap between passive data collection and active health management. By integrating data from wearables into its Knowledge Graph, NudgeRank™ can tailor its health nudges based on real-time data from users’ devices. For instance, if a wearable detects that a user’s physical activity has decreased over the past week, NudgeRank™ can immediately respond with personalized recommendations to get back on track—be it a reminder to take a walk or a nudge to join a local fitness challenge.

      Enhanced Personalization Through Continuous Feedback: The combination of wearables and NudgeRank™ offers a feedback loop that continuously refines and enhances the personalization of health interventions. Wearables provide the continuous stream of data needed to understand users’ behaviors in real time, while NudgeRank™ uses this data to generate and adjust nudges dynamically.

      This continuous feedback loop means that the more a user engages with their wearable and the NudgeRank™ system, the more personalized and effective the nudges become. For example, if a user consistently responds well to motivational nudges after a period of inactivity, the system will prioritize similar interventions in the future. This level of personalization can significantly enhance user engagement with their health goals, leading to better long-term outcomes.

      A New Paradigm for Digital Health Platforms: For the digital health industry, the integration of AI-driven systems like NudgeRank™ represents a new paradigm in how health interventions are delivered. No longer are digital health platforms simply repositories of data; they become active participants in the health management process, capable of delivering real-time, personalized interventions that are informed by the continuous flow of data from wearables.

      This shift has profound implications for the digital health industry:

      1. Increased User Engagement: As wearables and digital health platforms offer more personalized and effective interventions, user engagement is likely to increase. This not only benefits users by improving their health outcomes but also strengthens the value proposition of wearable and digital health products.

      2. Data-Driven Health Management: The integration of AI with wearable data enables a shift from reactive to proactive health management. Instead of waiting for users to encounter health issues, platforms can use predictive analytics to anticipate potential problems and intervene early, thereby reducing the risk of serious health events.

      3. Scalability and Reach: NudgeRank™ demonstrates that personalized health interventions can be delivered at scale. This is particularly important for global digital health platforms that cater to diverse populations with varying health needs. The ability to tailor interventions to each user, regardless of their location or specific health challenges, makes these platforms more effective and inclusive.

      4. Collaboration Opportunities: As AI-driven personalization becomes more sophisticated, there will be increasing opportunities for collaboration between wearable manufacturers, digital health platforms, and AI developers. These partnerships could lead to even more advanced health management solutions, combining the strengths of each industry to create integrated, seamless user experiences.

      The Road Ahead: What’s Next for NudgeRank™? 

      NudgeRank™ is already a powerful tool, but its potential is far from fully realized. The next frontier involves integrating Reinforcement Learning, allowing the system to not only suggest actions but to optimize these suggestions based on how patients respond. Imagine a system that doesn’t just learn from what you do today but adapts in real time to guide you toward better health tomorrow.

      There’s also the possibility of expanding NudgeRank™ into new areas of health. While it’s currently focused on physical activity, the underlying technology could be applied to a wide range of behaviors—diet, medication adherence, mental health support, and more. The modular design of NudgeRank™ means it can easily incorporate new data sources and goals, making it a versatile tool for any healthcare setting.

      Ethical Considerations and the Future of AI in Health Nudging

      As we continue to push the boundaries of what AI can achieve in healthcare, it’s crucial to pause and consider the ethical implications of these advancements. NudgeRank™ is a powerful tool, but with great power comes great responsibility. The integration of AI into health nudging raises important questions about privacy, fairness, and the transparency of machine learning models, especially in a field as sensitive as healthcare.

      Interpretable Machine Learning and Transparency: One of the key challenges in deploying AI systems in healthcare is ensuring that they are interpretable. Patients and healthcare providers need to understand how and why certain decisions are made, particularly when these decisions can significantly impact a person’s health. In the context of NudgeRank™, interpretability means that the system’s recommendations—whether it’s a nudge to exercise more or a reminder to take medication—must be explainable.

      Healthcare providers should be able to understand the reasoning behind each nudge, which in turn can help them trust the system and communicate more effectively with their patients. This transparency is not just a technical requirement but an ethical one, ensuring that AI supports informed decision-making rather than obscure or undermine it.

      Interpretable models are essential as they allow clinicians to see the factors that contributed to each recommendation. For instance, if NudgeRank™ suggests a particular health intervention, the model should be able to explain whether this suggestion was based on the patient’s recent activity levels, demographic data, or past responses to similar interventions. This level of clarity helps build trust in the AI system, both for clinicians and patients.

      Fairness in Healthcare AI: Another critical area of concern is fairness. AI systems have the potential to perpetuate or even exacerbate existing biases in healthcare. If not carefully designed, these systems could deliver different quality of care to different populations, reinforcing disparities rather than addressing them. Ensuring fairness in AI involves developing systems that are equitable across diverse patient populations.

      In NudgeRank™, fairness is addressed by ensuring that the system is trained on diverse datasets that represent a wide range of demographic and socioeconomic backgrounds. This diversity helps to prevent the model from becoming biased towards any particular group, ensuring that the health nudges it generates are equally effective for all users.

      However, fairness in AI goes beyond the data. It also involves continuously monitoring the system for any signs of bias and making adjustments as needed. For example, if the system’s nudges are found to be less effective for a particular demographic group, this issue needs to be addressed promptly, whether through retraining the model on more representative data or adjusting the algorithms to better account for the needs of that group.

      Privacy and Data Security: With the vast amounts of personal health data involved, privacy and data security are paramount. NudgeRank™ is built with robust data protection measures, including pseudonymization and encryption, ensuring that patient data is handled with the highest standards of confidentiality. This is particularly important in light of regulations like the General Data Protection Regulation (GDPR) in Europe and the Health Insurance Portability and Accountability Act (HIPAA) in the United States.

      Designing AI systems that respect patient autonomy is also crucial. Patients must be able to control how their data is used and opt-out of certain types of data collection or analysis. This respect for patient autonomy is essential for maintaining trust in AI-driven healthcare solutions.

      The Future of AI in Health Nudging: Looking ahead, the ethical deployment of AI in health nudging will require ongoing vigilance and commitment to principles of fairness, transparency, and privacy. As systems like NudgeRank™ become more integrated into everyday healthcare, it’s crucial that we continue to develop frameworks that ensure these technologies serve all patients equitably.

      The future of AI in health nudging is bright, but it must be guided by a strong ethical compass. By focusing on interpretability, fairness, and privacy, we can create systems that not only enhance health outcomes but do so in a way that is just, transparent, and respectful of patient autonomy.

      References: 

      1. Chiam, J., Lim, A., & Teredesai, A. (2024). NudgeRank: Digital Algorithmic Nudging for Personalized Health. Proceedings of KDD ’24, Barcelona, Spain.
      2. Chiam, J., Lim, A., Nott, C., Mark, N., Teredesai, A., & Shinde, S. (2024). Co-Pilot for Health: Personalized Algorithmic AI Nudging to Improve Health Outcomes. arXiv preprint arXiv:2401.10816.
      3. Topol, E. J. (2019). Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again. Basic Books.
      4. World Health Organization. (2022). Noncommunicable Diseases Progress Monitor. Retrieved from [https://www.who.int/news-room/fact-sheets/detail/noncommunicable-diseases](https://www.who.int/news-room/fact-sheets/detail/noncommunicable-diseases)
      5. Wang, H., Zhang, F., Wang, J., Zhao, M., Li, W., Xie, X., & Guo, M. (2018). Ripplenet: Propagating user preferences on the knowledge graph for recommender systems. In Proceedings of the 27th ACM international conference on information and knowledge management (pp. 417-426).
      6. Wang, H., Zhao, M., Xie, X., Li, W., & Guo, M. (2019). Knowledge graph convolutional networks for recommender systems. In The world wide web conference (pp. 3307-3313).
      7. Velickovic, P., Cucurull, G., Casanova, A., Romero, A., Lio, P., & Bengio, Y. (2017). Graph Attention Networks. arXiv preprint arXiv:1710.10903.
      8. Wang, X., He, X., Cao, Y., Liu, M., & Chua, T.-S. (2019). KGAT: Knowledge Graph Attention Network for Recommendation. Proceedings of the 25th ACM SIGKDD International Conference on Knowledge Discovery & Data Mining.

      Cuezen selected to participate in Microsoft for Startups Pegasus Program

      Designed for startups, the Pegasus Program by Microsoft provides crucial support to enhance revenue for selected companies that have already demonstrated product-market fit in industries like AI, healthcare and life sciences, cybersecurity, and retail. 

      CueZen has recently been chosen for the exclusive Microsoft for Startups Pegasus Program, highlighting our dedication to driving innovative advancements in healthcare technology and delivering personalized healthcare solutions.

      CueZen’s AI-powered personalization engine enhances individual health engagement by offering tailored recommendations throughout the care journey, helping people achieve their personal health objectives.  

      The Pegasus program allows us to bring advanced Open AI integration and Azure features to our customers and gives us increased access to Microsoft's enterprise health customer base, thereby expanding our global footprint together
      Ankur Teredesai
      CEO of CueZen and Professor at the University of Washington.

      HIMSS 2024

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      We’re excited to be attending HIMSS 2024 in Orlando, Florida, from 11-15 March 2024. This year, HIMSS is all about Creating Tomorrow’s Health. Everyone who matters in healthcare is there to discuss everything that’s shaping the future of healthtech. We look forward to all the conversations and can’t wait for you to discover how Cuezen is helping global Pharma, Provider, Payors, and HealthTech/smart wearables OEMs in Creating Tomorrow’s Health.

      Orthopedic Care

      Personalized Orthopedic Patient pathways with a surgeon-assigned care plan, continuous monitoring, engagement, and AI-based recommendations for patient engagement

      COPD

      Stratifying patients based on their risk for COPD, providing personalized nudges, and collecting data to power AI-driven pathways for diagnosis and treatment

      Clinical Trials

      Clinical Trial setup including segmentation, Adaptive Learning, Continuous Monitoring, Trial Adaptation. Personalization to improve patient engagement and medication adherence

      Come meet us and learn more about our innovative healthcare solutions for Orthopedic Care, COPD, Clinical Trials and more.
      Cuezen’s AI-based personalization engine for health delivers hyper-personalized nudges that drive behavior change, guiding individuals effectively through their unique health journeys toward positive health outcomes. Cuezen is at the forefront of the personalized healthcare revolution and was recently selected to the prestigious Microsoft for Startups Pegasus Program.

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        Titan Smart Wearables partners with CueZen to revolutionize health and wellness in India

        Going beyond counting steps and measuring BPM 

        Titan Smart Wearables recently announced their strategic partnership with CueZen with a shared vision to empower Indians with a new generation of smart wearables & AI-powered solutions that offer actionable guidance and support for a healthier lifestyle.

        “In light of the health challenges confronting India today, our collaboration is laser-focused on delivering customized solutions that cater to the diverse requirements of the Indian consumers. Leveraging the power of AI and wearable technology, Titan Smart Wearables and CueZen are committed to developing products and services that profoundly influence individuals’ fitness endeavors…” Ravi Kuppuraj. Business Head COO – Titan Smart Wearables.

        CueZen’s AI-driven personalization engine delivers hyper-personalized nudges and actionable recommendations encouraging lifestyle and behavioral change, significantly improving health outcomes and adherence to care protocols.

        “We must accept that most of us are highly irrational when it comes to prioritizing our lifestyle and health goals. A tiny bit of personalized nudging and engagement can go a long way to help our future self be a bit less irrational. Personalization is, therefore, the future of health. Our collaboration with Titan Smart Wearables leverages cutting-edge technology, fundamentals of behavioral economics, and AI-driven hyper-personalization to meet the diverse healthcare needs of India at nation scale,” said Ankur Teredesai, CEO of CueZen

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